IntegReview Ethical Review Board is an independent institutional review board (IRB) dedicated to providing unsurpassed ethical review services. The ethical principles employed by IntegReview that govern the conduct of human research are those identified in the Belmont Report; respect for persons, beneficence and justice. IntegReview is an institutional review board (IRB), also known as an independent ethics committee (IEC) or ethical review board (ERB), that has been formally designated to review, approve, and conduct periodic review of biomedical and behavioral research involving human subjects in the United States, Latin America and Canada. The Food and Drug Administration (FDA), Office for Human Research Protections (OHRP) and Health Canada regulations have empowered IRBs to approve, require modifications in planned research prior to approval, or disapprove research. IRBs are responsible for critical oversight functions for research conducted on human subjects that are scientific, ethical, and regulatory. IntegReview complies with the regulations as defined in the United States Food and Drug Administration (FDA), Code of Federal Regulations, Title 21, Parts 50, 54, 56, 312 and 812, International Conference on Harmonisation (ICH) Guidelines for Good Clinical Practices, E6, the Department of Health and Human Services (DHHS) regulations as identified in the Code of Federal Regulations, Title 45, Part 46, other regulations as applicable, as well as local and state laws. In November 2011, IntegReview established a Canadian Research Ethics Board (REB) to review research conducted in Canada in accordance with Health Canada’s Division 5, the TCPS 2 2nd Edition Tri-Council Policy Statement and the ICH Guidelines for Good Clinical Practice.