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EXCLUSIVE: MD Anderson President Ron DePinho Addresses Long-Term Cancer Strategies at IMM in Lisbon, Portugal

EXCLUSIVE: MD Anderson President Ron DePinho Addresses Long-Term Cancer Strategies at IMM in Lisbon, Portugal

During the recent Joint Conference on Gastric and Hereditary Cancer held at the Instituto de Medicina Molecular (IMM) in Lisbon, Portugal on November 20-21, MD Anderson’s President Ronald A. DePinho, M.D., gave a wide-ranging presentation entitled “Making Cancer History Together” that identified the serious threat that cancer poses and what MD Anderson is doing to address it. BioNews Texas Cancer News Editor Dr. ...

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MD Anderson Researchers Make Key Discovery on Tumor Growth Mechanics

MD Anderson Researchers Make Key Discovery on Tumor Growth Mechanics

A new study led by University of Texas MD Anderson Cancer Center researchers entitled “PKM2 phosphorylates MLC2 and regulates cytokinesis of tumor cells” shows that the pyruvate kinase M2 controls cell division – a finding with clear implications for tumor growth biology and therapeutics. The study was published in the journal Nature Communications. Pyruvate kinase M2 (PKM2) is highly expressed in tumors ...

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MD Anderson Researchers Discover Power Behind “Master” Cancer Gene

MD Anderson Researchers Discover Power Behind “Master” Cancer Gene

A novel study on the regulation of Myc entitled “CSN6 drives carcinogenesis by positively regulating ​Myc stability” was published in Nature Communications by Jian Chen, part of Dr. Mong-Hong Lee’s group in the Department of Molecular and Cellular Oncology at The University of Texas MD Anderson Cancer Center. In this study, the authors showed that Myc is a target of the COP9 signalosome ...

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MD Anderson Researchers Find Metabolic Reprogramming Leads To Tumor Regression

MD Anderson Researchers Find Metabolic Reprogramming Leads To Tumor Regression

In a study published this week in Nature entitled “IAPP-driven metabolic reprogramming induces regression of p53-deficient tumors in vivo,” a team of researchers led by Dr. Elsa Flores, associate professor of molecular and cellular oncology at MD Anderson Cancer Center, showed that the gene IAPP could potentially be used as therapeutics for tumors deficient in p53. The p53 is a transcription factor with a key role ...

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MD Anderson Gynecology Oncologist Gershenson Receives Excellence Award

MD Anderson Gynecology Oncologist Gershenson Receives Excellence Award

David M. Gershenson, M.D., has been given the Award of Excellence of the International Gynecology Cancer Society, as a recognition of his clinical, organizational, and scientific achievements regarding gynecologic oncology. The professor and former chair of the Department of Gynecologic Oncology and Reproductive Medicine at The University of Texas MD Anderson Cancer Center was presented with the award during a ceremony at the IGCS’s ...

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MD Anderson Study Shows Young Colorectal Cancer Patients to Nearly Double By 2030

MD Anderson Study Shows Young Colorectal Cancer Patients to Nearly Double By 2030

In a recent study entitled “Increasing Disparities in the Age-Related Incidences of Colon and Rectal Cancers in the United States, 1975-2010” published in JAMA Surgery, the authors report that while the incidence of colorectal cancer (CRC) has been decreasing in older patients, there is a significant increase of CRC incidence in young adults.  In this study, the team of researchers ...

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MD Anderson Boasts Two Years of Achievements For Moon Shots Program, Looks To Future

MD Anderson Boasts Two Years of Achievements For Moon Shots Program, Looks To Future

After just two years, the Moon Shots Program at The University of Texas MD Anderson Cancer Center has achieved several of its audacious initial goals, including improving the surgical outcomes in ovarian cancer patients, as well as fostering the development of new drug therapies. The program has been dedicated to advancing both molecular analysis and screening. “Our Moon Shots Program presses ...

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MD Anderson Study Finds Proton Therapy Less Costly Than Conventional Techniques For Early Stage Breast Cancer

MD Anderson Study Finds Proton Therapy Less Costly Than Conventional Techniques For Early Stage Breast Cancer

According to new research from The University of Texas MD Anderson Proton Therapy Center at Houston, early stage breast cancer patients may benefit from accelerated partial breast irradiation (APBI) using proton therapy as opposed to conventional whole breast irradiation (WBI) in terms of duration and cost of treatment. APBI is a localized form of radiation treatment (brachytherapy) that involves the ...

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Two More MD Anderson Leaders Elected to the Institute of Medicine

Two More MD Anderson Leaders Elected to the Institute of Medicine

A pair of accomplished healthcare industry leaders from the University of Texas MD Anderson Cancer Center have just been appointed to head separate departments at the National Academies‘ Institute of Medicine (IOM). The two have made immeasurable contributions to the field of medicine and health, and MD Anderson believes that they are sure to bring about more change and improvements from ...

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Entire Lobe Of Lung Removal More Effective Than Partial Resection To Early-Stage Lung Cancer Patients

Entire Lobe Of Lung Removal More Effective Than Partial Resection To Early-Stage Lung Cancer Patients

According to a recent study from The University of Texas MD Anderson Cancer Center, the removal of the entire lobe of the lung in patients with early-stage lung cancer, rather than the partial resection, may offer better overall survival. In addition, stereotactic ablative radiotherapy (SABR) may offer the exact same survival benefit as a lobectomy for some patients. Published in JAMA Surgery, it is the largest population ...

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Genomic Heterogeneity Varies Across Different Cancers, MD Anderson Study Suggests

Genomic Heterogeneity Varies Across Different Cancers, MD Anderson Study Suggests

Two years ago, a study on renal cell cancer became a turning point in the way oncologists viewed the efficacy of drawing a biopsy from only one region of a tumor. The findings suggested this method did not allow a comprehensive enough representation of all the cancer-driving genetic abnormalities needed to properly examine the tumor. Just recently, however, a team ...

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CPRIT-Funded MD Anderson, University of Houston Cancer Initiative Targets Smoking Cessation in Mental Health Patients

CPRIT-Funded MD Anderson, University of Houston Cancer Initiative Targets Smoking Cessation in Mental Health Patients

A partnership between MD Anderson and anti-tobacco programs led by the University of Houston and Austin Travis County Integral Care (ATCIC) is currently underway to extend cancer prevention efforts. As part of the effort, researchers are focused on educating mental health providers to help tobacco users eliminate their addiction within mental health facilities. There are 19 Local Mental Health Authorities ...

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MD Anderson Adds 15 New Members to Board of Visitors

MD Anderson Adds 15 New Members to Board of Visitors

The University of Texas MD Anderson Cancer Center is at the forefront of personalized, cutting edge cancer care. It is also supports comprehensive and novel research and development efforts from some of the most accomplished scientists and academics in the country. To further its mission to eradicate cancer in the state of Texas, the country, and the rest of the ...

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MD Anderson Study Finds Cancer Cells Adapt Energy Needs to Metastasize to Other Organs

MD Anderson Study Finds Cancer Cells Adapt Energy Needs to Metastasize to Other Organs

Houston’s University of Texas MD Anderson Cancer Center says that if you want to understand why cancer cells metastasize — think of Sparta, the Greek city-state that as a political and military power spanned the cusp of the bronze and early iron ages from about 650 BC to the Roman conquest in 146 BC. Spartan warriors were fed a special ...

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Prominent Radiation Oncologist Joins MD Anderson

Prominent Radiation Oncologist Joins MD Anderson

It is estimated that almost two-thirds of cancer patients will receive radiation therapy (RT) during the course of their disease. This underscores the importance of constantly providing the healthcare system with advanced technology, and personalized, evidence-based approaches to treating cancer with RT. The University of Texas MD Anderson Cancer Center has a new head of the division of radiation oncology, ...

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Breast Conservation Therapy May Be Better than a Mastectomy, According to MD Anderson Researchers

Breast Conservation Therapy May Be Better than a Mastectomy, According to MD Anderson Researchers

Among the most commonly diagnosed cancer, and most prevalent cause of cancer death in women is breast cancer; estimated to affect 1 out of every 8 women. Out of the approximately 220,000 American women who will be diagnosed with breast cancer this year, 40,000 will die of it. Even with today’s cutting edge research technology, much remains to be discovered about ...

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MD Anderson Scientists Find Novel Immunotherapy/Vaccine Combo Decreases HER2 Positive Breast Cancer Recurrence

MD Anderson Scientists Find Novel Immunotherapy/Vaccine Combo Decreases HER2 Positive Breast Cancer Recurrence

Research findings to be presented by The University of Texas MD Anderson Cancer Center at the American Society of Clinical Oncology’s 2014 Breast Cancer Symposium in San Francisco report that a new vaccine candidate for treating breast cancer, known as GP2, has been shown to inhibit the recurrence of the disease according to recent studies. The vaccines were shown to ...

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MD Anderson Reports Proton Beam Therapy is Cheaper than IMRT in Long Run For Some Cancers

MD Anderson Reports Proton Beam Therapy is Cheaper than IMRT in Long Run For Some Cancers

An international manhunt for a five-year-old UK cancer patient whose parents sought out cutting-edge proton beam radiation therapy in Spain, against the wishes of UK public health authorities, has highlighted the rise of next-generation radiation therapy technologies that are more accurate and expose patients to less radiation. In response to an increase in interest about proton beam therapy, scientists from ...

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Memorial Hermann and MD Anderson to Expand Breast Screening and Care in Greater Houston

Memorial Hermann and MD Anderson to Expand Breast Screening and Care in Greater Houston

The Memorial Hermann Health System, together with The University of Texas MD Anderson Cancer Center, has just announced a new collaboration aimed at introducing an innovative method of breast screening that will be accessible to the community of breast care centers in Houston, Texas. Towards the end of November 2014, MD Anderson will officially be the sole source of professional breast ...

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New MD Anderson and Foundation Medicine Trial Focuses on Targeted Therapies For Metastatic Disease

New MD Anderson and Foundation Medicine Trial Focuses on Targeted Therapies For Metastatic Disease

The University of Texas MD Anderson Cancer Center recently partnered with Cambridge-based Foundation Medicine to conduct a clinical trial that will determine whether targeted therapies selected based on tumor molecular profiling leads to longer survival among patients with metastatic disease, compared to therapies that weren’t selected through this method. The study, entitled, Initiative for Molecular Profiling and Advanced Cancer Therapy, also known as “IMPACT2,” ...

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MD Anderson Breast Cancer Program Welcomes New Recruits

MD Anderson Breast Cancer Program Welcomes New Recruits

The Department of Breast Medical Oncology at MD Anderson has announced the addition of two new members to its team: Debu Tripathy, M.D., who will serve as the new department chair, and V. Craig Jordan, Ph.D., the developer of a number of proven cancer therapies. The two new recruits will be joining MD Anderson officially this Fall. One of Jordan’s ...

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Prostate Cancer Prevention Trial Studies Factors That Influence Men to Undergo Biopsies

Prostate Cancer Prevention Trial Studies Factors That Influence Men to Undergo Biopsies

SW—OG, a National Cancer Institute supported organization that conducts clinical trials in adult cancers, recently completed a study called the Prostate Cancer Prevention Trial, which revealed that healthy male participants that went through all the necessary steps of the trial have a higher likelihood of undergoing a preventive biopsy. This study, entitled “Factors Associated with Adherence to an End-of-Study Biopsy: Lessons from ...

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BCM, MD Anderson Study Highlights Genetic Alterations Found In An Aggressive Breast Cancer Subtype

BCM, MD Anderson Study Highlights Genetic Alterations Found In An Aggressive Breast Cancer Subtype

Researchers from the Lester and Sue Smith Breast Center at Baylor College of Medicine and the University of Texas MD Anderson Cancer Center have identified genetic alterations thought to contribute to the development of more aggressive forms of breast cancer. The study, entitled “Recurrent ​ESR1–​CCDC170 rearrangements in an aggressive subset of ​estrogen receptor-positive breast cancers,” was published in the acclaimed journal Nature Communications and led by ...

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MD Anderson Researcher Involved in I-Spy Trial Supports pCR Effect in Cancer Treatment

MD Anderson Researcher Involved in I-Spy Trial Supports pCR Effect in Cancer Treatment

Cancer researcher Don Berry, PhD, from the University of Texas M.D. Anderson Cancer Center recently weighed in on the results taken from the Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization (ALTTO) trial fallout, which have generated controversy among the medical and pharmaceutical community. The ALTTO study showed that when lapatinib (Tykerb/Tyverb) is added to the standard form of trastuzumab (also known as Herceptin) ...

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