The International Anesthesia Research Society (IARS) awarded four promising, young investigators with $600,000 worth of new 2014 IARS Mentored Research Awards. Among them, the IARS grants program awarded Rene Przkora, MD, PhD, of the University of Texas Medical Branch at Galveston $150,000 in grants for his work on anesthesia used in hip joint replacement surgeries.
“Preconditioning of Older Patients Undergoing Hip Joint Replacement Surgery” is Przkora’s awarded project, which explores the role of anesthesiology in relation to hip replacement surgery from the preoperative period through to the surgery’s end, a project that IARS considers to be an important step in strengthening the specialty as well as supporting the surgical home concept. Przkora focused on this theme in his research in response to the fact that joint replacement surgery is becoming more common, and not only performed in the case of cancer or cardiovascular diseases.
In addition to Dr. Przkora, Miles Berger, MD, PhD, of Duke University Medical Center was also awarded a grant for his role in the first prospective clinical study to determine the long-term trajectory and significance of perioperative changes in Alzheimer’s disease biomarkers. In his study, the researcher correlated Alzheimer’s disease biomarker changes with ones related to cognitive function and brain connectivity.
Awardee Minjae Kim, MD, of Columbia University Medical Center is the author of the project “Assessing preoperative comorbidities through latent class analysis,” in which the researcher analyzed patterns of comorbidities as well as risk factors associated with adverse preoperative outcomes in patients. His research focuses on the lack of information and identification of combinations of comorbidities present in surgical patients in the current methods of risk stratification.
“Anesthesia-induced impairments of developmental synaptic plasticity,” authored by awardee Nadia Lunardi, MD, PhD, of the University of Virginia School of Medicine focuses on the organization and function of surviving synapses, following a GA-induced development apoptosis. Her research sought to decipher the mechanisms of GA-induced impairment of developmental synaptic transmission and contribute to the development of tools that can target its causative pathways and provide safer anesthesia.
“These applications were submitted by outstanding, well-trained candidates who were under the tutelage of excellent mentors. In addition, the sponsoring institutions are providing substantial support to the candidates,” explained Piyush Patel, MD, FRCPC, Professor of the Department of Anesthesiology at the University of California, San Diego.
Each of the four grants given to the young researchers are designed to further contribute to the understanding of clinical practice in anesthesiology, and to fuel independent research funding. The society has already granted more than $14 million to anesthesia research programs over the last thirty years.